By DAN GOREMAN Associated PressDALLAS (AP) A gene that is passed on to your offspring is transmitted to the next generation by DNA, and scientists are racing to understand how it happens.
Researchers are exploring the possibility that an inherited gene that makes it easier for a mother to carry out the body’s natural response to a cold is the cause of the disease.
The new study was published in the journal Nature Genetics.
It suggests that the gene, called SLC45A3, plays a role in the development of multiple forms of cold-related cancers.
Scientists have long suspected that the SLC-45A gene is involved in a range of diseases, including colds, asthma and some forms of cancer.
Researchers said they found the gene to be associated with the development and spread of many different types of cancers, including cancers of the pancreas, breast, liver and skin.
The research team looked at the genes of 1,800 people in four U.S. counties and found that SLC44A1, SLC43A1 and SLC46A1 were all found in more than 80 percent of the cases.
Those genes were all associated with cancers of breast, colon and prostate.
The researchers found that genes that were more common in people with advanced cancers were more likely to be found in people who had colds.
“Our findings suggest that SSCA3A1 plays a significant role in this syndrome,” said lead author Dr. Stephen R. Licht, of the University of Texas Medical Branch at Galveston, in an emailed statement.
The researchers did not identify any genetic markers that could be linked to the disease in the group.
The gene is part of the same family as a family member of the SSC enzyme that is crucial for the body to make vitamin D. Scientists think the SCC-3A2 gene plays a similar role.
The SLC23A2 protein is the same enzyme that causes the vitamin D production in the body.
Dr. Lichts group also found that colds are associated with increased susceptibility to lung cancer, a form of lung cancer that can cause pneumonia.
In the new study, the researchers identified a genetic variant in SLC35A that was linked to about one in 10 cases of cancer in the same people.
The variant is called S35A1 or S35S.
“We identified that S35 is associated with both a higher risk of lung cancers and increased susceptibility for pneumonia in a cohort of more than 1,000 adults,” Dr. Lochts said.
“We also identified that the variant is a strong predictor of lung-specific lung cancers in those with asthma.”SLC35 is one of the genes that plays a major role in lung cancer and asthma,” Dr Licht said.
He noted that there is currently no known way to treat the disease without reducing the frequency of the gene.”
This is a huge problem,” he said.
The SLC3A gene, which codes for a protein called a transcription factor, controls the enzyme that produces vitamin D in the cells of the body, which are called the skin and lung.
It also controls the synthesis of other proteins, such as collagen and adipose tissue.
The findings may help scientists better understand how the gene affects the disease and how it spreads.
The study was funded by the National Institutes of Health and by the Centers for Disease Control and Prevention.