Genetic drift, the phenomenon whereby some individuals carry a mutation from one generation to the next, is often linked to population growth.
A recent study by researchers at the University of Texas, Austin, and the University at Buffalo in New York, published in the Proceedings of the National Academy of Sciences, suggests that genetic drift has also occurred in the past, but that these migrations were not linked to the spread of the disease.
In their paper, the researchers used a genome-wide association study to identify a single person whose DNA was shared by at least 13 other people.
They then performed genetic tests to test for genetic drift in these 13 people and compared their genomes to a set of closely related individuals from the same family, and to those from other families with similar DNA profiles.
The researchers found that the genetic drift was statistically significant in the two families, but not in the other three families.
“Genetic drift can be difficult to detect in the general population,” said study coauthor Jana Jokic, a professor in the Department of Genetics and Genetics Science at the UT Austin College of Arts and Sciences.
“It’s very difficult to tell how much genetic drift there is because of the large number of people that we’re looking at.”
Genetic Drift in Human HistoryThe researchers examined how many people from a single family in Spain and Italy had inherited a single copy of the same mutation from their parents.
They found that roughly 50% of the individuals in the families had it, and they estimated that the mutation contributed to a small but statistically significant fraction of the population’s genetic variation.
“This finding is significant because it shows that the common genetic ancestry among individuals in Spain, Italy, and Spain is very low,” Jokics said.
“In fact, the average genetic ancestry of the Spanish, Italian, and Spanish-speaking populations is less than 5% each.”
The average genetic drift between families in Spain is estimated at about 3%, while that for Italy and Spain, respectively, is about 10%.
“This is a very interesting finding because, for all the talk about genetic drift and population growth, it’s really hard to detect genetic drift,” Joksic said.
To confirm that genetic mutation is indeed driving the population movement, the UT researchers ran another experiment using the same DNA profile to compare the genomes of a different set of people.
The results showed that genetic variation between the three families was higher in the three different groups of individuals, suggesting that the same genetic drift is causing genetic drift.
“The more closely related we are to one another, the more we have a genetic signal that the person is carrying the mutation,” Jaksic said, adding that she expects genetic drift to continue.
“If you have an individual from the other family that has the mutation, they are going to have an advantage over their neighbor.
This means that the population will be growing, and that will increase the genetic variation that we see between individuals.”
In their study, the scientists looked at the genomes and DNA profiles of 12 individuals from 13 families. “
I hope that our study will provide insight into the genetic history of the human population and help us better understand human disease and how it has affected the human genome.”
In their study, the scientists looked at the genomes and DNA profiles of 12 individuals from 13 families.
They used genetic tests, including a comparison of the DNA of a group of people from different populations to a single, complete person.
They also used a genealogy analysis to map out the genetic origins of the people who shared their genomes.
“We didn’t look at what the DNA in the genome says about the people,” Joka said.
Instead, they looked at what genetic information about the individual matches what the individuals share in common.
“The results show that the genes in the individuals were very similar, but the people were not,” Jokinics said, noting that her study focused on genetic drift rather than migration.