Genetically testing your dog will help you determine whether they have blue or white eyes, or some other genetic condition.
The condition is known as Mendelian disorders, or mitochondrial disorders, and it affects between 2 percent and 4 percent of the population.
Mendelians are hereditary defects that occur in the DNA of the dog’s parents.
When these mutations occur, the dog will have two copies of each of the genetic code, a characteristic called chromosome number.
“When a mutation occurs, that changes the sequence of DNA, the number of letters, and that alters the way genes work,” said Dr. Michael Zaremba, a molecular genetics expert and professor at the University of Southern California’s Davis School of Veterinary Medicine.
A red blood cell test for blue eyesGenealogy.comBlue-eyed dogs are thought to have an almost 100 percent chance of having blue eyes.
If you have a dog with blue eyes who has a mutation that causes the same condition as a dog that has white eyes and a mutation to one of the genes, you may be at an increased risk of having the condition.
If your dog has blue eyes and has one of these mitochondrial disorders and you have one of your dog’s mitochondria mutations, you are more likely to have blue-eyed or white-eyed eyes than if your dog does not have these mitochondrial abnormalities.
The mitochondria are small pieces of DNA that make up mitochondria.
You can read more about mitochondria here.
If you have white eyes with a red blood cells test, you’re at an even greater risk of developing blue- or white eye, Zaremla said.
“The blue-eye mutation is associated with mitochondrial abnormalities, so it’s a marker of that, which is why a white eye mutation could be associated with blue- and white-eye,” he said.
Zaremlas dog mitochondrial test results show the dog had white eyes at birth, which can indicate a genetic condition that is inherited in your family.
“This is the first genetic marker that’s been proven to be predictive of blue eyes,” he added.
The dog was tested for a genetic mutation to two of the most common genes involved in the development of blue and white eyes.
The dog also had the mutation in its mitochondrial DNA, which could indicate a mitochondrial disorder.
This mutation is linked to a mutation in the mitochondrial genes that controls the function of the eye cells in the eye.
The mutation also causes an abnormal production of red blood corpuscles, which are the blood vessels that carry oxygen to the eye, and is associated in part with certain eye conditions.
Dr. Mark Gansler, a cardiologist at the Cleveland Clinic and professor of medicine at the Johns Hopkins University School of Medicine, said this mutation may be linked to some of the symptoms associated with white-sightedness, such as an inability to see the colors of the sky and the ability to blink quickly.
Gansler said the test for this mutation is a good test for predicting the risk of mitochondrial disorders.
“In the past, it was used to screen for certain types of mutations, but that wasn’t good enough to show that people with these conditions had the condition,” he explained.
“Now, we can test for these mutations and if they’re associated with a mitochondrial condition, we know it’s related to this.”
Zarembas dog was healthy at the time of his test.
But now, his dog has been diagnosed with a mutation associated with the condition and has been tested for the mutation and the red blood test to see if it’s causing the condition in his dog.
If the dog has the red-blood test result and the mitochondrial mutations, he has a 10 percent chance that he will develop the condition as well.
But if the dog does have both the red and mitochondrial tests, it is still at a 10 to 20 percent risk of the condition developing.
Zrembas lab has been able to determine the mutation at the level of his dog’s DNA, but not the level at which the dog was born.
The next step is to test the dog for other mutations.
If the mutation is related to the mitochondrial disorders at birth and is linked with the white-and-blue eyes, the test will be accurate at detecting the mutation, said Zremba.
A dog with white eyesGenealogical.com”We can be very accurate when we are measuring the mutations in the dog,” Zremlas said.
“It’s a very specific test.
If we can identify that mutation, we’ll be able to get the correct result and then be able determine if the mutation causes the condition.”
If you or someone you know has a dog who has blue- eyes, you can get the test at AncestryDNA.org or by calling 1-800-872-2766.
To learn more about dog genetics and how DNA testing can help you find your dog, check out the ABC News video